This script is to combat the frustration of navigating all over the place when opening, saving, or changing Explorer folders when most of what you want to do is in ONE FOLDER.
But you have to jump back and forth between apps - say Excel, Outlook, Acrobat, Word - and each has its own idea as to where you should be saving things.
Other people have posted similar scripts, I'm sure. I think Quick Access Popup has a similar feature, but I haven't checked it out.
Ctrl+Win+S: From most open/save dialogs or an open Explorer window, save a folder path.
Ctrl+Win+C: Clear that folder path.
Ctrl+Win+J: Jump to that folder.
Ctrl+Win+Q: Ask the script what folder you have set.
Shift+Escape: Bail out.
Tested so far on Win7, 64-bit, AHK_H 64-bit, 1.1.26.01, 1.1.28.00 (AHK_H and AHK_L). Works with:
[Update 12/16/17] Word, Excel, Powerpoint, Acrobat, Explorer, Thunderbird,Scite4AutoHotkey, Outlook, Notepad, Firefox 57, IE 11, Pale Moon 27 (32-bit), Chrome (from Ctrl+S)
I'm sure many progs will choke on it (Edit March 27, 2018 - chokes less)
[Update March 27, 2018 - chokes less on Thunderbird and Office Open/Save/Attach dialogs]
[Update March 28, 2018 - can now set the persistent folder from T-bird Save As and Attach dialogs]
*Still to do: Fix intermittent Acrobat bugs.
Though it's called PersistentSaveFolder, that isn't a complete description - you can jump to the Save folder in Explorer also.